Abstract: The organic loading of sediments with shrimp monoculture and shrimp - tilapia mixed - culture was investi gated by the relative poiutant indexes ( Ap ) of tiiree multij^le contamination factors N, S and P in 18 experimental enclosures (the area: 36 m2) . These enclosures were divided into six groups, and each group has three parallels. All of the enclosures were put in 3 000 young shrimps ( Penaeusvannameii with the bodylength of (0.45 ±0.01 ) cm, in which ", I , $ , % , & and V enclosure groups were allowed to be stocked with 0, 4, 8, 12, 18 and 24 tilapias (OreochromismossambicusS with the body weight of (201 ±25) g respectively after one month. There was not water - exchange done in all of the enclosures during the experimental process. The experiment period was 70 d. The experimental results showed as follows : 1) The contents of N, P and S increased obviously in sediments with the culture time lasting. However, the rate of increase in shrimp - tilapia mixed - culture enclosures was less than that in shrimp monoculture enclosures. 2) The values of Ipfollowed the order: "(10.78) > V(8.30) > I (7.68) >&(7.40) > $(6.09) >% (4.12), and the value of Ip of group III was significant lower than that of group "(P <0• 05).Therefore, it can be concluded that polyculture of shrimp at the level of 8. 3 X 105 ind/hm2 and tilapia at the level of 3 320 in^^hm2demonstrated the best ecological advantage. The present study provides a reference in shrimp - tilapia carrying capacity management. [ Chinese Fishery Quality and Standards, 2015 , 5 (3 ):8 - 12 ]